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alpha-msh peptide
- 品牌:ABBIOTEC
- 产地:美国
- 货号:350043
- 价格: ¥询价/5 mg
- 发布日期: 2019-07-31
- 更新日期: 2024-03-19
产品详请
产地 | 美国 |
品牌 | ABBIOTEC |
货号 | 350043 |
保存条件 | store at -20°C |
保质期 | 两年个月 |
MSH (melanocyte-stimulating hormone), produced by the pituitary gland, regulates the pigmentation of the skin by increasing melanin production in melanocytes. Alpha-MSH corresponds to aa 138-150 of corticotropin precursor (pro-opiomelanocortin, POMC). Alpha-MSH is an endogenous melanocortin receptor agonist (Ki values are 0.12, 31, 660 and 5700 nM for MC1, MC3, MC4 and MC5 receptors respectively). Alpha-MSH is an anti-inflammatory peptide which antagonizes proinflammatory mediators, including TNF-alpha, IL-6 and NO, and induces anti-inflammatory cytokine IL-10. It also inhibits food intake and induces penole erections following i.c.v. administration.Human: Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2 or Ac-SYSMEHFRWGKPV-NH2