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- 品牌:ABBIOTEC
- 产地:美国
- 货号:350019
- 发布日期: 2019-11-25
- 更新日期: 2024-05-08
产地 | 美国 |
品牌 | ABBIOTEC |
货号 | 350019 |
纯度 | % |
Adrenocorticotropic hormone (ACTH), also known as corticotropin, is produced and secreted by the anterior pituitary gland. ACTH is an important component of the hypothalamic-pituitary-adrenal axis as a response to biological stress. ACTH secretion is triggered by the corticotropin-releasing hormone (CRH) released from the hypothalamus, and stimulates the adrenal glands to release corticosteroids such as cortisol. ACTH [1-39] corresponds to full-length ACTH. ACTH [1-24] is conserved across species and is 75% as potent as ACTH. ACTH [1-10] has no ACTH activity but alter blood pressure. ACTH [4-10] has neurological effects.Human: H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-OH or H-SYSMEHFRWGKPV-OH
促肾上腺皮质激素(ACTH)ACTH为腺垂体分泌的微量多肽激素,是肾上腺皮质活性的主要调节者。测定ACTH有助于判断下丘脑一垂体一肾上腺皮质的功能状态 [1] 。相关项目包括黄体生成素、卯泡刺激素、孕酮、雌二醇、雌三醇、泌乳素。促肾上腺皮质激素,简称ACTH,是从牲畜(猪、牛、羊等)的脑下垂体前叶中提取的一种激素类药物。它能刺激肾上腺皮质分泌多种肾上腺皮质激素。促肾上腺皮质激素是一种旦白质,分子量约为2000,等电点47左右,易溶于水及希醇中,不溶于*等有机溶剂。它具有较强的耐热性,在酸性溶液中甚稳定,但在碱性溶液中极易破坏。