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camkii [290-309] inhibitory peptide
- 品牌:ABBIOTEC
- 产地:美国
- 货号:350006
- 价格: ¥询价/1 mg
- 发布日期: 2019-07-31
- 更新日期: 2024-04-25
产品详请
产地 | 美国 |
品牌 | ABBIOTEC |
货号 | 350006 |
保存条件 | store at -20°C |
保质期 | 两年个月 |
This peptide is a potent calmodulin antagonist and an inhibitor for calcium/calmodulin-dependent protein kinase II (CaMKII), which belongs to the CAMK Ser/Thr protein kinase family. The sequence derives from the residues 290-309 within the calmodulin-binding domain of human CaMKII alpha. CaMKII is a prominent kinase in the central nervous system that functions in long-term potentiation and neurotransmitter release. This peptide inhibits CaMKII activation by blocking calmodulin binding to CaMKII.Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala or LKKFNARRKLKGAILTTMLA