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OAT-1(mouse)抗体
物品单位 品牌
Abbiotec
  • 产地:美国
  • 货号:250798
  • 发布日期: 2021-01-15
  • 更新日期: 2021-01-15
产品详细说明
CAS编号
抗体名 OAT-1
是否单克隆
靶点
用途范围 E, IHC, WB
形态 Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 50% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide.
宿主 Rabbit
标记物
纯度 %
免疫原 KLH-conjugated synthetic peptide encompassing a sequence within the center region of mouse OAT-1.
产地 美国
品牌 Abbiotec
货号 250798
保存条件 -20℃
应用范围 E, IHC, WB
抗原来源
保质期 一年
规格 0.1mg
产品用途 科研
克隆性
适应物种 M R
亚型 IgG
标识物
浓度 %
是否进口

产品背景Description 

The organic anion transporter 1 (OAT-1 or SLC22A6) is localized to the basolateral membrane of renal tubular epithelial cells and plays a critical role in the excretion and detoxification of anionic compounds. OAT-1 functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). OAT-1 mediates the sodium-independant uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS), p-aminohippurate (PAH), ochratoxin (OTA), acyclovir (ACV) and many other organic compounds.



别名Alternate Names 

Solute carrier family 22 member 6; Organic anion transporter 1; OAT1; Renal organic anion transporter 1; ROAT1; Novel kidney transcript; NKT; SLC22A6



应用说明Application Notes 

E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500


引用文献Product Citations 

[1] Naud J et al. 2011. Drug Metabolism and Disposition. 39(8):1363-1369. PMID# 21525170. [2] Eisner C et al. 2012. Kidney International. 77:519-526. PMID# 20032962.