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| 产地 | 美国 |
| 品牌 | Abbiotec |
| 货号 | 251175 |
| 保存条件 | -20℃ |
| 用途 | 科研 |
| 应用范围 | E, IHC, WB |
| 抗原来源 | |
| CAS编号 | |
| 保质期 | 一年 |
| 抗体名 | CD45 |
| 是否单克隆 | 否 |
| 克隆性 | |
| 靶点 | |
| 适应物种 | H M R |
| 形态 | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. |
| 宿主 | Rabbit |
| 标记物 | |
| 包装规格 | 0.1mg |
| 纯度 | % |
| 亚型 | IgG |
| 标识物 | |
| 浓度 | % |
| 免疫原 | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CD45. |
| 是否进口 | 是 |
产品背景Description
The CD45 antigen (Receptor-type tyrosine-protein phosphatase C, PTPRC) is a protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. CD45 acts as a positive regulator of T-cell coactivation upon binding to DPP4. Defects in CD45 are a cause of severe combined immunodefiency autosomal recessive T-cell negative/B-cell-positive/NK-cell-positive (T-B+NK+ SCID). Genetic variations in CD45 are involved in multiple sclerosis susceptibility.
别名Alternate Names
Leukocyte common antigen; L-CA; T200; CD45 antigen; PTPRC; Receptor-type tyrosine-protein phosphatase C; CD45
应用说明Application Notes
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
引用文献Product Citations
[1] Karaca T et al. 2015. Iran J Basic Med Sci. 18(4): 370-379. PMID 26019800. [2] Karaca T et al. 2011. Allergologia Immunopathologia. 40(6): 357-361. PMID 22115572.
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