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- 品牌:Abbiotec
- 产地:美国
- 货号:251175
- 发布日期: 2021-01-15
- 更新日期: 2023-12-05
抗体名 | CD45 |
是否单克隆 | 否 |
用途范围 | E, IHC, WB |
形态 | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. |
宿主 | Rabbit |
纯度 | % |
免疫原 | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CD45. |
产地 | 美国 |
品牌 | Abbiotec |
货号 | 251175 |
保存条件 | -20℃ |
应用范围 | E, IHC, WB |
保质期 | 一年 |
规格 | 0.1mg |
产品用途 | 科研 |
适应物种 | H M R |
亚型 | IgG |
浓度 | % |
是否进口 | 是 |
产品背景Description
The CD45 antigen (Receptor-type tyrosine-protein phosphatase C, PTPRC) is a protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. CD45 acts as a positive regulator of T-cell coactivation upon binding to DPP4. Defects in CD45 are a cause of severe combined immunodefiency autosomal recessive T-cell negative/B-cell-positive/NK-cell-positive (T-B+NK+ SCID). Genetic variations in CD45 are involved in multiple sclerosis susceptibility.
别名Alternate Names
Leukocyte common antigen; L-CA; T200; CD45 antigen; PTPRC; Receptor-type tyrosine-protein phosphatase C; CD45
应用说明Application Notes
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
引用文献Product Citations
[1] Karaca T et al. 2015. Iran J Basic Med Sci. 18(4): 370-379. PMID 26019800. [2] Karaca T et al. 2011. Allergologia Immunopathologia. 40(6): 357-361. PMID 22115572.