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产地 | 美国 |
品牌 | Abbiotec |
货号 | 250761 |
保存条件 | -20℃ |
用途 | 科研 |
应用范围 | E, IHC, WB |
抗原来源 | |
CAS编号 | |
保质期 | 一年 |
抗体名 | MTR-1A |
是否单克隆 | 否 |
克隆性 | |
靶点 | |
适应物种 | B H M R Sh |
形态 | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. |
宿主 | Rabbit |
标记物 | |
包装规格 | 0.1mg |
纯度 | % |
亚型 | IgG |
标识物 | |
浓度 | % |
免疫原 | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human MTR-1A. |
是否进口 | 是 |
产品背景Description
Melatonin receptor-1A (MTR-1A) is a high affinity receptor for melatonin, which mediates the reproductive and circadian actions of melatonin. MTR-1A activity is mediated by pertussis toxin sensitive G-proteins that inhibit adenylate cyclase activity. MTR-1A is expressed in hypophyseal pars tuberalis and hypothalamic suprachiasmatic nuclei (SCN). MTR-1A belongs to the G-protein coupled receptor 1 family.
别名Alternate Names
Melatonin receptor type 1A; Mel1a melatonin receptor; Mel-1A-R; MTNR1A; MTR1A
应用说明Application Notes
E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500
引用文献Product Citations
[1] Kang NH et al. 2016. Brain Res. 1652: 89-96. PMID 27693415. [2] Wang S et al. 2012. Pain. 153(120): 2448-57. PMID 23046768. [3] Peliciari-Garcia R et al. 2011. Chronobiology International. 28(1): 21-30. PMID 21182401. [4] Ahn S et al. 2011. Auris nasus Larynx. 39(5): 479-483. PMID 22055508. [5] Corthell JT. et al. 2013. Neuroscience. PMID 24365461. [6] Huang F et al. 2013. Neural Regeneration Research. 8(32): 2991-3002.