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产地 | 美国 |
品牌 | Abbiotec |
货号 | 251403 |
保存条件 | -20℃ |
用途 | 科研 |
应用范围 | E, IHC, WB |
抗原来源 | |
CAS编号 | |
保质期 | 一年 |
抗体名 | CD225 |
是否单克隆 | 否 |
克隆性 | |
靶点 | |
适应物种 | B H M R |
形态 | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. |
宿主 | Rabbit |
标记物 | |
包装规格 | 0.1mg |
纯度 | % |
亚型 | IgG |
标识物 | |
浓度 | % |
免疫原 | KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD225. |
是否进口 | 是 |
产品背景Description
Interferon-induced transmembrane protein 1 (CD225) is an IFN-induced antiviral protein that mediates cellular innate immunity to major human pathogens, namely influenza A H1N1 virus, SARS-CoV, West Nile virus, Ebola virus and dengue virus by inhibiting the early step(s) of replication. CD225 plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. CD225 is implicated in the control of cell growth. CD225 is a component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals.
别名Alternate Names
IFITM1; interferon-induced transmembrane protein 1; CD225; Interferon-inducible protein 9-27; Interferon-induced protein 17; Leu-13 antigen;IFI17
应用说明Application Notes
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500