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| 产地 | 美国 |
| 品牌 | Abbiotec |
| 货号 | 251640 |
| 保存条件 | -20℃ |
| 用途 | 科研 |
| 应用范围 | E, IHC, WB |
| 抗原来源 | |
| CAS编号 | |
| 保质期 | 一年 |
| 抗体名 | 8-OHdG |
| 是否单克隆 | 否 |
| 克隆性 | |
| 靶点 | |
| 适应物种 | H M R |
| 形态 | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. |
| 宿主 | Rabbit |
| 标记物 | |
| 包装规格 | 0.1mg |
| 纯度 | % |
| 亚型 | IgG |
| 标识物 | |
| 浓度 | % |
| 免疫原 | KLH-conjugated 8-OHdG. |
| 是否进口 | 是 |
产品背景Description
8-hydroxydeoxyguanosine (8-OHdG) is a modified base indicative of DNA damage associated with mutagenesis and carcinogenesis. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually lead to several diseases in humans, such as atherosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions such as Alzheimer’s disease.
别名Alternate Names
8-OHdG; 8-oxoguanine; 8-hydroxy-2-deoxyguanine; 8-oxyguanosine; 7,8-Dihydro-8-oxo-2'-deoxyguanosine;7,8-Dihydro-8-oxodeoxyguanosine; 8-Hydroxy-2'-deoxyguanosine;8-Hydroxydeoxyguanosine; 8-Oxo-2'-deoxyguanosine; 8-Oxo-7,8-dihydro-2'-deoxyguanosine; 8-Oxo-7,8-dihydrodeoxyguanosine; 8-Oxo-dG
应用说明Application Notes
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
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