Cathelicidin antimicrobial peptides are effectors of innate immune defense in mammals. Humans and mice have only one cathelicidin gene, whereas domesticated mammals such as the pig, cow, and horse have multiple cathelicidin genes. The porcine cathelicidin peptide PR-39 is a 39aa peptide that acts additively with human cathelicidin LL-37 to kill group A Streptococcus. PR-39 Peptide also stimulates angiogenesis and inhibits inflammatory responses by selectively blocking proteasome degradation of IkBa.Porcine: H-RRRPRPPYLPRPRPPPFFPPRLPPRIPPGFPPRFPPRFP-NH2