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peptide p60
  • 品牌:ABBIOTEC
  • 产地:美国
  • 货号:350582
  • cas:1319725-20-6
  • 发布日期: 2019-07-31
  • 更新日期: 2025-05-09
产品详请
产地 美国
品牌 ABBIOTEC
货号 350582
保存条件 store at -20°C
英文名称
CAS编号
保质期 两年个月
Peptide P60 has demonstrated potential of inhibiting the immunosuppressive activity of murine and human derived regulatory T-cells (Tregs) and enhances the effector T-cell stimulation in vitro by binding to regulatory T-cells specific forkhead/winged helix transcription factor 3 (FOXP3). Peptide P60 can enter the cells to inhibit FOXP3 nuclear translocation and activity on other transcription factors. In vitro, peptide P60 (100 uM) inhibited murine and human-derived Treg and improved effector T cell stimulation.H-Arg-Asp-Phe-Gln-Ser-Phe-Arg-Lys-Met-Trp-Pro-Phe-Phe-Ala-Met-OH or H-RDFQSFRKMWPFFAM-OH
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