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peptide p60
物品单位 | 价格 | 品牌 |
---|---|---|
1 mg | 询价 | ABBIOTEC |
- 产地:美国
- 货号:350582
- 发布日期: 2019-07-31
- 更新日期: 2023-06-06
产品详细说明
产地 | 美国 |
品牌 | ABBIOTEC |
货号 | 350582 |
保存条件 | store at -20°C |
英文名称 | |
CAS编号 | |
保质期 | 两年个月 |
Peptide P60 has demonstrated potential of inhibiting the immunosuppressive activity of murine and human derived regulatory T-cells (Tregs) and enhances the effector T-cell stimulation in vitro by binding to regulatory T-cells specific forkhead/winged helix transcription factor 3 (FOXP3). Peptide P60 can enter the cells to inhibit FOXP3 nuclear translocation and activity on other transcription factors. In vitro, peptide P60 (100 uM) inhibited murine and human-derived Treg and improved effector T cell stimulation.H-Arg-Asp-Phe-Gln-Ser-Phe-Arg-Lys-Met-Trp-Pro-Phe-Phe-Ala-Met-OH or H-RDFQSFRKMWPFFAM-OH