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timp-3 peptide
- 品牌:ABBIOTEC
- 产地:美国
- 货号:350574
- 价格: ¥询价/0.1 mg
- 发布日期: 2019-07-31
- 更新日期: 2024-04-25
产品详请
产地 | 美国 |
品牌 | ABBIOTEC |
货号 | 350574 |
保存条件 | store at -20°C |
保质期 | 两年个月 |
Tissue inhibitor of metalloproteinases 3 (TIMP-3) binds to metalloproteinases such as collagenases and irreversibly inactivates the proteases. TIMP-2 is involved in the extracellular matrix remodeling by binding to MMP-1, -2, -3, -7, -9, -13, -14 and -15. Defects in TIMP-3 are the cause of Sorsby fundus dystrophy (SFD), a macular disorder leading to vision loss.The synthetic peptide used to raise the antibody Cat. No. 250885 is selected from a sequence within the C-term region of human TIMP-3. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.