Calpain 3 is a calcium regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.The synthetic peptide used to raise the antibody Cat. No. 200193 is selected from a sequence within the N-term region of Calpain-3. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.