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slicer peptide
物品单位 | 价格 | 品牌 |
---|---|---|
0.1 mg | 询价 | ABBIOTEC |
- 产地:美国
- 货号:350549
- 发布日期: 2019-07-31
- 更新日期: 2023-06-07
产品详细说明
产地 | 美国 |
品牌 | ABBIOTEC |
货号 | 350549 |
保存条件 | store at -20°C |
英文名称 | |
CAS编号 | |
保质期 | 两年个月 |
Eukaryotic translation initiation factor 2C 2, also known as Slicer protein or Argonaute-2, provides endonuclease activity to RNA-induced silencing complexes (RISC). Slicer cleaves siRNA/mRNA heteroduplexes bound to RISC. Slicer is essential for embryonic development and RNA-mediated gene silencing (RNAi). Slicer is localised in processing bodies (P bodies) that contain decapping enzymes, a 5'-to-3' exoribonuclease, LSm proteins, and RNAi machinery components.The synthetic peptide used to raise the antibody Cat. No. 200187 is selected from a sequence within the N-term region of human Slicer. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.