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ocrl1 peptide
物品单位 价格 品牌
0.1 mg 询价 ABBIOTEC
  • 产地:美国
  • 货号:350539
  • 发布日期: 2019-07-31
  • 更新日期: 2019-07-31
产品详细说明
产地 美国
品牌 ABBIOTEC
货号 350539
保存条件 store at -20°C
英文名称
CAS编号
保质期 两年个月
Inositol polyphosphate 5-phosphatase (OCRL1) converts phosphatidylinositol 4,5-biphosphate to phosphatidylinositol 4-phosphate. The enzyme also converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate. The enzyme is involved in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with lysosomes. Defects in OCRL1 are the cause of Lowe syndrome, a multisystem disorder affecting eyes, nervous system and kidney, and Dent disease type 2, a renal disease.The synthetic peptide used to raise the antibody Cat. No. 200177 is selected from a sequence within the C-term region of human OCRL1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.