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ocrl1 peptide
物品单位 | 价格 | 品牌 |
---|---|---|
0.1 mg | 询价 | ABBIOTEC |
- 产地:美国
- 货号:350539
- 发布日期: 2019-07-31
- 更新日期: 2023-03-31
产品详细说明
产地 | 美国 |
品牌 | ABBIOTEC |
货号 | 350539 |
保存条件 | store at -20°C |
英文名称 | |
CAS编号 | |
保质期 | 两年个月 |
Inositol polyphosphate 5-phosphatase (OCRL1) converts phosphatidylinositol 4,5-biphosphate to phosphatidylinositol 4-phosphate. The enzyme also converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate. The enzyme is involved in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with lysosomes. Defects in OCRL1 are the cause of Lowe syndrome, a multisystem disorder affecting eyes, nervous system and kidney, and Dent disease type 2, a renal disease.The synthetic peptide used to raise the antibody Cat. No. 200177 is selected from a sequence within the C-term region of human OCRL1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.