RAC-alpha serine/threonine-protein kinase (AKT1) signals downstream of phosphatidylinositol 3-kinase (PI3K) to mediate the effects of various growth factors such as PDGF, EGF, and IGF-I. This antibody may cross-react with AKT1, 2 and 3.The synthetic peptide used to raise the antibody Cat. No. 200172 is selected from a sequence within the C-term region of human AKT. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.