Alpha-type platelet-derived growth factor receptor (PDGFRA), a tyrosine protein kinase, is a receptor that binds both PDGFA and PDGFB. A fusion of PDGFRA and FIP1L1 due to an interstitial chromosomal deletion is the cause of some cases of hypereosinophilic syndrome.The synthetic peptide used to raise the antibody Cat. No. 200170 is selected from a sequence within the C-term region of human PDGFRA. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.