Xeroderma pigmentosum group C-complementing protein (XPC) is involved in DNA excision repair by recognizing DNA damage and altering chromatin structure for damage-processing enzymes. Defects in XPC are a cause of xeroderma pigmentosum complementation group C characterized by solar sensitivity and skin cancer predisposition.The synthetic peptide used to raise the antibody Cat. No. 200169 is selected from a sequence within the C-term region of human XPC. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.