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mlh1 peptide
  • 品牌:ABBIOTEC
  • 产地:美国
  • 货号:350529
  • 发布日期: 2019-07-31
  • 更新日期: 2025-05-09
产品详请
产地 美国
品牌 ABBIOTEC
货号 350529
保存条件 store at -20°C
英文名称
CAS编号
保质期 两年个月
DNA mismatch repair protein Mlh1 (MLH1) is involved in the repair of DNA mismatches. MLH1 is part of the BRCA1-associated genome surveillance complex (BASC), which contains BRCA1, MSH2, MSH6, MLH1, ATM, BLM, PMS2 and the RAD50-MRE11-NBS1 protein complex. Defects in MLH1 are the cause of hereditary non-polyposis colorectal cancer type 2, Turcot syndrome, Muir-Torre syndrome, including brain, colorectal, breast and endometrial tumors.The synthetic peptide used to raise the antibody Cat. No. 200167 is selected from a sequence within the C-term region of human MLH1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
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