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mlh1 peptide
物品单位 | 价格 | 品牌 |
---|---|---|
0.1 mg | 询价 | ABBIOTEC |
- 产地:美国
- 货号:350529
- 发布日期: 2019-07-31
- 更新日期: 2023-03-20
产品详细说明
产地 | 美国 |
品牌 | ABBIOTEC |
货号 | 350529 |
保存条件 | store at -20°C |
英文名称 | |
CAS编号 | |
保质期 | 两年个月 |
DNA mismatch repair protein Mlh1 (MLH1) is involved in the repair of DNA mismatches. MLH1 is part of the BRCA1-associated genome surveillance complex (BASC), which contains BRCA1, MSH2, MSH6, MLH1, ATM, BLM, PMS2 and the RAD50-MRE11-NBS1 protein complex. Defects in MLH1 are the cause of hereditary non-polyposis colorectal cancer type 2, Turcot syndrome, Muir-Torre syndrome, including brain, colorectal, breast and endometrial tumors.The synthetic peptide used to raise the antibody Cat. No. 200167 is selected from a sequence within the C-term region of human MLH1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.