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fancl peptide
- 品牌:ABBIOTEC
- 产地:美国
- 货号:350524
- 价格: ¥询价/0.1 mg
- 发布日期: 2019-07-31
- 更新日期: 2024-03-29
产品详请
产地 | 美国 |
品牌 | ABBIOTEC |
货号 | 350524 |
保存条件 | store at -20°C |
保质期 | 两年个月 |
Fanconi anemia group L protein (FANCL) is an ubiquitin ligase that mediates ubiquitination of FANCD2, a key step in the DNA damage pathway. FANCL is required for proper primordial germ cell proliferation in the embryonic stage. Defects in FANCA are the cause of Fanconi anemia, a syndrome characterized by pancytopenia, congenital malformations and predisposition to cancers caused by a hypersensitivity to DNA-damaging agents, chromosomal instability and defective DNA repair.The synthetic peptide used to raise the antibody Cat. No. 200162 is selected from a sequence within the N-term region of human FANCL. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.