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atm peptide
物品单位 价格 品牌
0.1 mg 询价 ABBIOTEC
  • 产地:美国
  • 货号:350520
  • 发布日期: 2019-07-31
  • 更新日期: 2019-07-31
产品详细说明
产地 美国
品牌 ABBIOTEC
货号 350520
保存条件 store at -20°C
英文名称
CAS编号
保质期 两年个月
Ataxia telangiectasia mutated (ATM) is a Ser/Thr protein kinase which activates checkpoint signaling upon double strand breaks, apoptosis and genotoxic stresses such as ionizing ultraviolet A light, thereby acting as a DNA damage sensor. ATM is also involved in signal transduction and cell cycle control and may function as a tumor suppressor. Defects in ATM are the cause of ataxia telangiectasia, leukemia, and lymphoma.The synthetic peptide used to raise the antibody Cat. No. 200158 is selected from a sequence within the center region of human ATM. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.