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atm peptide
- 品牌:ABBIOTEC
- 产地:美国
- 货号:350520
- 价格: ¥询价/0.1 mg
- 发布日期: 2019-07-31
- 更新日期: 2023-11-28
产品详请
产地 | 美国 |
品牌 | ABBIOTEC |
货号 | 350520 |
保存条件 | store at -20°C |
保质期 | 两年个月 |
Ataxia telangiectasia mutated (ATM) is a Ser/Thr protein kinase which activates checkpoint signaling upon double strand breaks, apoptosis and genotoxic stresses such as ionizing ultraviolet A light, thereby acting as a DNA damage sensor. ATM is also involved in signal transduction and cell cycle control and may function as a tumor suppressor. Defects in ATM are the cause of ataxia telangiectasia, leukemia, and lymphoma.The synthetic peptide used to raise the antibody Cat. No. 200158 is selected from a sequence within the center region of human ATM. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.