Menin (MEN1) is involved in DNA repair by interacting with FANCD2 and DBF4. Defects in MEN1 are the cause of parathyroid gland tumors.The synthetic peptide used to raise the antibody Cat. No. 200152 is selected from a sequence within the C-term region of human menin. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.