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e-cadherin peptide
物品单位 | 价格 | 品牌 |
---|---|---|
0.1 mg | 询价 | ABBIOTEC |
- 产地:美国
- 货号:350496
- 发布日期: 2019-07-31
- 更新日期: 2023-06-07
产品详细说明
产地 | 美国 |
品牌 | ABBIOTEC |
货号 | 350496 |
保存条件 | store at -20°C |
英文名称 | |
CAS编号 | |
保质期 | 两年个月 |
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. E-cadherin (CDH1) is involved in mechanisms regulating cell-cell adhesion, mobility and proliferation of epithelial cells. CDH1 has a potent invasive suppressor role. CDH1 binds to integrin alpha-E/beta-7. Defects in CDH1 are the cause of gastric, endometrial, breast, ovary and thyroid cancers. This antibody may cross-react with cadherin-2, 3 and 4.The synthetic peptide used to raise the antibody Cat. No. 200134 is selected from a sequence within the C-term region of human E-cadherin. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.