e-cadherin peptide
- 发布日期: 2019-07-31
- 更新日期: 2025-05-09
产品详请
产地 |
美国
|
品牌 |
ABBIOTEC
|
货号 |
350496
|
保存条件 |
store at -20°C
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英文名称 |
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CAS编号 |
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保质期 |
两年个月
|
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. E-cadherin (CDH1) is involved in mechanisms regulating cell-cell adhesion, mobility and proliferation of epithelial cells. CDH1 has a potent invasive suppressor role. CDH1 binds to integrin alpha-E/beta-7. Defects in CDH1 are the cause of gastric, endometrial, breast, ovary and thyroid cancers. This antibody may cross-react with cadherin-2, 3 and 4.The synthetic peptide used to raise the antibody Cat. No. 200134 is selected from a sequence within the C-term region of human E-cadherin. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.