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apc peptide
- 品牌:ABBIOTEC
- 产地:美国
- 货号:350494
- 价格: ¥询价/0.1 mg
- 发布日期: 2019-07-31
- 更新日期: 2024-07-26
产品详请
产地 | 美国 |
品牌 | ABBIOTEC |
货号 | 350494 |
保存条件 | store at -20°C |
保质期 | 两年个月 |
The adenomatous polyposis coli protein (APC) is a tumor suppressor that promotes rapid degradation of catenin-beta 1 (CTNNB1) and participates in Wnt signaling. The GSK3-beta protein kinase regulates its activity by phosphorylation. APC binds to PDZ domains of DLG1 and 3, to catenins, axin and MAPRE protein family including the EB members.The synthetic peptide used to raise the antibody Cat. No. 200132 is selected from a sequence within the N-term region of human APC. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.