LRRK2 is involved in the phosphorylation of proteins central to Parkinson disease. Defects in LRRK2 are the cause of Parkinson disease 8 (PARK8).The synthetic peptide used to raise the antibody Cat. No. 200115 is selected from a sequence within the C-term region of human LRRK2. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.