HGFR (MET), a tyrosine protein kinase, is the receptor for the hepatocyte growth factor and scater factor. Activation of HGFR after rearrangement with the TPR gene produces an oncogenic protein c-MET. Defects in HGFR/MET are a cause of hepatocellular carcinoma and renal carcinoma.The synthetic peptide used to raise the antibody Cat. No. 200113 is selected from a sequence within the N-term region of human HGFR. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.