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insr peptide
物品单位 | 价格 | 品牌 |
---|---|---|
0.1 mg | 询价 | ABBIOTEC |
- 产地:美国
- 货号:350472
- 发布日期: 2019-07-31
- 更新日期: 2023-03-31
产品详细说明
产地 | 美国 |
品牌 | ABBIOTEC |
货号 | 350472 |
保存条件 | store at -20°C |
英文名称 | |
CAS编号 | |
保质期 | 两年个月 |
INSR binds insulin and has a tyrosine protein kinase activity. The short isoform has a higher affinity for insulin. The receptor mediates the metabolic functions of insulin. The receptor binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). Defects in INSR are the cause of insulin resistance.The synthetic peptide used to raise the antibody Cat. No. 200110 is selected from a sequence within the N-term region of human INSR. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.