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syvn1 peptide
物品单位 价格 品牌
0.1 mg 询价 ABBIOTEC
  • 产地:美国
  • 货号:350470
  • 发布日期: 2019-07-31
  • 更新日期: 2019-07-31
产品详细说明
产地 美国
品牌 ABBIOTEC
货号 350470
保存条件 store at -20°C
英文名称
CAS编号
保质期 两年个月
Synoviolin (SYVN1) acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates subsequently promoting their degradation. For instance, SYVN1 protects neurons from apoptosis induced by polyglutamine-expanded huntingtin (HTT) or unfolded GPR37 by promoting their degradation. SYVN1 is up-regulated in synovial tissues from patients with rheumatoid arthritis.The synthetic peptide used to raise the antibody Cat. No. 200108 is selected from a sequence within the C-term region of human SYVN1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.