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syvn1 peptide
物品单位 | 价格 | 品牌 |
---|---|---|
0.1 mg | 询价 | ABBIOTEC |
- 产地:美国
- 货号:350470
- 发布日期: 2019-07-31
- 更新日期: 2023-06-07
产品详细说明
产地 | 美国 |
品牌 | ABBIOTEC |
货号 | 350470 |
保存条件 | store at -20°C |
英文名称 | |
CAS编号 | |
保质期 | 两年个月 |
Synoviolin (SYVN1) acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates subsequently promoting their degradation. For instance, SYVN1 protects neurons from apoptosis induced by polyglutamine-expanded huntingtin (HTT) or unfolded GPR37 by promoting their degradation. SYVN1 is up-regulated in synovial tissues from patients with rheumatoid arthritis.The synthetic peptide used to raise the antibody Cat. No. 200108 is selected from a sequence within the C-term region of human SYVN1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.