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alpha-conotoxin imi peptide
| 物品单位 | 价格 | 品牌 |
|---|---|---|
| 1 mg | 询价 | ABBIOTEC |
- 产地：美国
- 货号：350460
- 发布日期： 2019-07-31
- 更新日期： 2023-06-06
产品详细说明
| 产地 | 美国 |
| 品牌 | ABBIOTEC |
| 货号 | 350460 |
| 保存条件 | store at -20°C |
| 英文名称 | |
| CAS编号 | |
| 保质期 | 两年个月 |
Alpha-conotoxin IMI is a 12-aa toxin isolated from the cone snail Conus imperialis venom. Alpha-conotoxin IMI is a potent blocker of the alpha/delta nicotinic acetylcholine channel receptors (nAChR) located on postsynaptic membranes. Alpha-conotoxin IMI inhibits in a voltage independent manner mammalian neuronal nAChRs (a3/b2 > a7 > a3/b4) and has no effect on nAChRs composed of a2/b2, a3/b2, a4/b2, a2/b4, a3/b4, or a4/b4 subunits. This toxin is highly active against the neuromuscular receptor in frog.H-Gly-Cys-Cys-Ser-Asp-Pro-Arg-Cys-Ala-Trp-Arg-Cys-NH2 (Cys2-Cys8, Cys3-Cys12) or H-GCCSDPRCAWRC-NH2 (Cys2-Cys8, Cys3-Cys12)
