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alpha-conotoxin imi peptide
物品单位 价格 品牌
1 mg 询价 ABBIOTEC
  • 产地:美国
  • 货号:350460
  • 发布日期: 2019-07-31
  • 更新日期: 2019-07-31
产品详细说明
产地 美国
品牌 ABBIOTEC
货号 350460
保存条件 store at -20°C
英文名称
CAS编号
保质期 两年个月
Alpha-conotoxin IMI is a 12-aa toxin isolated from the cone snail Conus imperialis venom. Alpha-conotoxin IMI is a potent blocker of the alpha/delta nicotinic acetylcholine channel receptors (nAChR) located on postsynaptic membranes. Alpha-conotoxin IMI inhibits in a voltage independent manner mammalian neuronal nAChRs (a3/b2 > a7 > a3/b4) and has no effect on nAChRs composed of a2/b2, a3/b2, a4/b2, a2/b4, a3/b4, or a4/b4 subunits. This toxin is highly active against the neuromuscular receptor in frog.H-Gly-Cys-Cys-Ser-Asp-Pro-Arg-Cys-Ala-Trp-Arg-Cys-NH2 (Cys2-Cys8, Cys3-Cys12) or H-GCCSDPRCAWRC-NH2 (Cys2-Cys8, Cys3-Cys12)