RF-NH2 peptide belongs to a group of RFamide peptides, which have an arginine-phenylalanine-amide structure at the C-term end. RF-NH2 shares a similar C-term sequence with neuropeptide FF (NPFF) and have a relatively high affinity to GPR147 (also called NPFF1 receptor, RFRP receptor or OT7T022).H-Arg-Phe-NH2 or H-RF-NH2