mart-1 [27-35] peptide
- 发布日期: 2019-07-31
- 更新日期: 2025-05-29
产品详请
产地 |
美国
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品牌 |
ABBIOTEC
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货号 |
350267
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保存条件 |
store at -20°C
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英文名称 |
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CAS编号 |
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保质期 |
两年个月
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MART-1 (Melanoma antigen recognized by T-cells 1) is a melanocyte differentiation antigen recognized by the cytotoxic T-lymphocytes. MART-1 is only found in melanoma, melanocyte cell lines and the retina. MART-1 is involved in melanosome biogenesis by ensuring the stability of GPR143. It plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes. MART-1 [27-35] sequence is a very common immunogenic epitope for HLA-A2-restricted melanoma-specific tumor-infiltrating lymphocytes (TIL) and may be useful for the development of immunotherapeutic strategies.Human: H-Ala-Ala-Gly-Ile-Gly-Ile-Leu-Thr-Val-OH or H-AAGIGILTV-OH