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oat-1 peptide
- 品牌:ABBIOTEC
- 产地:美国
- 货号:300115
- 价格: ¥询价/0.1 mg
- 发布日期: 2019-07-31
- 更新日期: 2024-05-17
产品详请
产地 | 美国 |
品牌 | ABBIOTEC |
货号 | 300115 |
保存条件 | store at -20°C |
保质期 | 两年个月 |
The organic anion transporter 1 (OAT-1 or SLC22A6) is localized to the basolateral membrane of renal tubular epithelial cells and plays a critical role in the excretion and detoxification of anionic compounds. OAT-1 functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). OAT-1 mediates the sodium-independant uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS), p-aminohippurate (PAH), ochratoxin (OTA), acyclovir (ACV) and many other organic compounds. The synthetic peptide used to raise the antibody Cat. No. 250797 is selected from a sequence within the center region of human OAT-1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.