Basic fibroblast growth factor (bFGF or FGF2), also called heparin-binding growth factor 2 is an angiogenic agent in vivo and potent mitogen for a variety of cell types in vitro. bFGF activates the MAP kinase signaling pathway and plays a role in synaptic transmission. In additon bFGF induces cell proliferation and binds heparin more strongly than aFGF.The synthetic peptide used to raise the antibody Cat. No. 250559 is selected from a sequence within the center region of human bFGF. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.