Cytokeratin 19 
背景描述Description：
细胞角蛋白19(CK19)在上皮组织胞浆内的细胞骨架中形成中间丝，并提供机械支持。抗细胞角蛋白19染色上皮和上皮，如，，*癌，胆道癌，和。细胞角蛋白19是区分和肝内胆管细胞癌的有用指标。细胞角蛋白7、CAM5.21、Ber-Ep4/MOC31、HepPar1和TTF1联合染色可促进这种分化。细胞角蛋白19染色也可用于甲状腺乳头状癌的鉴别。
Cytokeratin 19 (CK19) forms intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue and provides mechanical support. Anti-Cytokeratin 19 stains epithelia and epithelial malignancies such as carcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Cytokeratin 19 is a useful marker for distinguishing hepatocellular carcinoma from intrahepatic cholangiocarcinoma. This differentiation is improved when stained in combination with Cytokeratin 7, CAM5.2l, Ber-EP4/MOC31, HepPar1 and TTF1. Cytokeratin 19 staining can also be used to recognize thyroid papillary carcinomas.

Specifications：
Clone IHC019
Source Mouse Monoclonal
Positive Control Bladder, Colon Carcinoma, Colon, Thyroid Carcinoma
Dilution Range 1:50-1:200

参考文献References：
Jain R, et al. Appl Immunohistochem Mol Morphol. 2010; 18:9-15.
Rosai J. Tumori. 2003; 89:517-9.
de Matos LL, et al. Diagn Pathol. 2012; 7:97.