Collagen Type IV

背景描述Description：
Ⅳ型胶原是基底膜的主要成分，可作为观察基底膜是否存在和检查其结构的标志。除上皮基底层外，抗Ⅳ型胶原染色间充质成分。它有助于鉴别软组织，包括神经鞘瘤和平滑肌瘤。抗Ⅳ型胶原抗体在分化良好、恶性后常与这些组织发生反应。在研究的成分、外皮细胞瘤、和上皮样内皮瘤时，抗Ⅳ型胶原蛋白的应用比非特异性的银网状染色法产生更可靠的结果。
Collagen Type IV is a primary component in the basal lamina that is used as a marker to observe the presence of the lamina and examine its structure. In addition to the epithelial basal lamina, Anti-Collagen Type IV stains mesenchymal components. It is useful for identifying soft tissue cancers including schwannomas and leiomyomas. Anti-Collagen Type IV frequently reacts with these tissues after becoming well-differentiated and malignant. The use of Anti-Collagen Type IV produces more reliable results than non-specific silver reticulum stains when investigating the vascular elements of neoplasms, hemangiopericytoma, angiosarcoma and epithelioid hemangioendothelioma.

Specifications：
Clone IHC549
Source Mouse Monoclonal
Positive Control Lung, Muscle
Dilution Range 1:50-1:200

参考文献References:
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