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产地 | 中国 |
品牌 | GenomeMe |
货号 | IHC402 |
保存条件 | 2-8℃ |
英文名称 | CDX-2 |
保质期 | 2年个月 |
CDX-2
背景描述Description:
CDX-2是肠上皮细胞表达的一种与尾相关的同源盒转录因子。CDX-2是一种有用的胃肠道标记物,可用于确定胃肠道转移性腺癌和类癌的起源。抗CDX-2可用于鉴别肺腺癌和转移性大肠腺癌,而卵巢黏液性癌也可与抗CDX-2呈阳性反应,从而限制了与转移性大肠腺癌的鉴别能力。
CDX-2 is a caudal-related homeobox transcription factor that is expressed by intestinal epithelial cells. CDX-2 is a useful marker for gastrointestinal carcinoma, and for determining the origin of gastrointestinal metastatic adenocarcinoma and carcinoids. Anti-CDX-2 is used for differentiating lung and metastatic colorectal adenocarcinoma, however mucinous ovarian carcinoma also react positively with Anti-CDX-2, thereby limiting the ability to differentiate from metastatic colorectal adenocarcinoma.
Specifications
Clone IHC402
Source Mouse Monoclonal
Positive Control Colon
Dilution Range 1:50-1:200
参考文献References:
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Liu Q, et al. Mod Pathol. 2007; 20:1286–97.
Mazziotta RM, et al. Appl Immunohistochem Mol Morphol. 2005; 13:55-60.
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Werling RW, et al. Am J Surg Pathol. 2003; 27:303-10.
Scholl C, et al. J Clin Invest. 2007; 117:1037–48.