产品货号Reference:              CAN-FTE-6080
检测方法Kit Type:                 Competitive LIA
规格Kit Size:                         96-well break-apart microplate
灵敏度Sensitivity:                 0.17 pg/mL
检测样本Sample Type:         Human serum / 25 μL
校准范围Calibrator Range:  0.25–125 pg/mL
检测时间Total Assay Time:  90 minutes
背景介绍：
睾酮是一种C-19类固醇，男性从睾丸和肾上腺皮质分泌，女性从肾上腺皮质和卵巢分泌。睾酮也是由雄烯二酮的外周组织产生的，这在男性中没有什么生理意义，但在女性中，大约有一半的循环睾酮是从这个来源产生的。睾酮测量主要用于男性减退和女性高雄激素状态的临床评估。
睾酮在血液中循环与三种蛋白质结合：性激素结合球蛋白(60-80%)、白蛋白和皮质醇结合球蛋白。只有大约1-2%的总循环睾酮保持不受约束或自由。尽管目前仍在研究中，但大多数研究人员都接受将游离睾酮测定作为生物活性成分的一种衡量标准。建议采用游离睾酮测定，以克服运输蛋白变化对总睾酮浓度的影响。
Testosterone is a C-19 steroid secreted from the testis and the adrenal cortex in men and from the adrenal cortex and ovaries in women. Testosterone is also produced by peripheral tissues from androstenedione, which is of little physiological signi? cance in men, however in women about half of the circulating testosterone is derived from this origin. Testosterone measurements are used mainly for clinical evaluation of hypogonadism in males and hyper-androgenic states in females.
Testosterone circulates in the blood bound to three proteins: sex hormone binding globulin (60–80%), albumin and cortisol binding globulin. Only about 1–2% of the total circulating testosterone remains unbound or free. Even though it is still under investigation, most researchers accept the free testosterone determination as a measure of the biologically active fraction. Free testosterone determinations are recommended to overcome the influences caused by variations in transport proteins on the total testosterone concentration.

注：本产品仅用于科研用途，不能直接用于人体或临床诊断使用。