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产地 | 加拿大 |
品牌 | Diagnostics Biochem Canada, Inc. |
货号 | CAN-B-4300 |
检测限 | 0.1 mg/L |
数量 | 96孔/盒 |
检测方法 | ELISA |
标记物 | |
样本 | 血清 |
应用 |
产品货号Reference: CAN-B-4300
检测方法Kit Type: Competitive ELISA
规格Kit Size: 96-well break-apart microplate
灵敏度Sensitivity: 0.1 mg/L
检测样本Sample Type: Human serum / 20 μL
校准范围Calibrator Range: 0.2–10 mg/L
检测时间Total Assay Time: 80 minutes
背景介绍:
β2-微球蛋白是一条由10 0个氨基酸组成的单肽链,存在于有核细胞表面。β-2-M被持续分泌到循环系统中,从而维持一个平衡的血清水平。
诊断意义:
肾小球滤过率的降低导致β2-微球蛋白水平的升高。
β2-微球蛋白是诊断*疾病和活动期的有用指标。
获得性综合征(Acquired Immune de?ciency syndrome,AIDS)患者血清β-2-M水平升高。
检测的血清样本总数为92份,在男性、前和后女性的正常水平之间差异不大。男性样本的平均值为1.582 mg/L,前女性的平均值为1.457 mg/L,后女性的平均值为1.608 mg/L,青年人的平均值为1.13 mg/L。
β2-Microglobulin (β2-M) is a single polypeptide chain containing 100 amino acids and is found on the surface of nucleated cells. β2-M is continuously secreted into the circulatory system and therefore maintains a balanced serum level.
Clinical Trends:
Decreases in the glomerular ?ltration rate gives rise to increases in the level of β2-M.
β2-M is a helpful marker in the diagnosis of kidney disease and active rheumatoid arthritis.
Patients with acquired immune de?ciency syndrome (AIDS) show an increased level of β2-M.
β2-M has a low concentration in serum. We have found in a normal unselected population that in serum the highest level for β2-M is 3.8 mg/L. The total number of serum samples tested was 92, showing little differences in the normal level in males, pre- and postmenopausal females. The average for male samples = 1.582 mg/L, for premenopausal female = 1.457 mg/L, for postmenopausal female = 1.608 mg/L and ?nally for young people = 1.13 mg/L.