产品货号Reference:             CAN-AD-208
检测方法Kit Type:                Competitive ELISA
规格Kit Size:                         96-well break-apart microplate
灵敏度Sensitivity:                 0.04 ng/mL
检测样本Sample Type:          Human serum / 25 μL
检测范围Calibrator Range:   0.1–10 ng/mL
检测时间Total Assay Time:   80 minutes

背景介绍：

雄烯二酮是由肾上腺和性腺产生的。因此，血清中雄烯二酮水平的测定对评价这些腺体的功能状态具有重要意义。雄烯二酮是睾酮和雌酮的前体。在女性中除了肾上腺外，卵巢也是雄烯二酮的重要来源。据报道，雄烯二酮在排卵周期中呈逐日波动的趋势。女性睾酮的主要产生来自于其他相关雄激素的转化，尤其是雄烯二酮。女性睾丸异常应伴有血清雄烯二酮水平的测定。血清睾酮的测定与雄烯二酮的酶免疫测定相结合，可用来确定雄激素过量产生的来源是肾上腺还是卵巢。
Androstenedione is produced by the adrenals and gonads. As a result, the determination of the level of androstenedione in serum is important in the evaluation of the functional state of these glands. Androstenedione is a precursor of testosterone and estrone. Besides the adrenals, in females, the ovaries have been shown to be an important source of androstenedione. It has been reported that there is a fluctuation day by day of androstenedione during the ovulatory cycle.The principle production of testosterone in females is from the conversion of other related androgens, especially androstenedione. An abnormal testosterone level in women should be accompanied by the estimation of serum androstenedione. The use of serum testosterone determination in conjunction with the enzyme immunoassay of androstenedione can be used to determine if the source of the excess androgen production is adrenal or ovarian.