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peptide p60
- 品牌:ABBIOTEC
- 产地:美国
- 货号:350582
- 价格: ¥询价/1 mg
- 发布日期: 2019-07-31
- 更新日期: 2024-04-24
产品详请
产地 | 美国 |
品牌 | ABBIOTEC |
货号 | 350582 |
保存条件 | store at -20°C |
保质期 | 两年个月 |
Peptide P60 has demonstrated potential of inhibiting the immunosuppressive activity of murine and human derived regulatory T-cells (Tregs) and enhances the effector T-cell stimulation in vitro by binding to regulatory T-cells specific forkhead/winged helix transcription factor 3 (FOXP3). Peptide P60 can enter the cells to inhibit FOXP3 nuclear translocation and activity on other transcription factors. In vitro, peptide P60 (100 uM) inhibited murine and human-derived Treg and improved effector T cell stimulation.H-Arg-Asp-Phe-Gln-Ser-Phe-Arg-Lys-Met-Trp-Pro-Phe-Phe-Ala-Met-OH or H-RDFQSFRKMWPFFAM-OH