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pka inhibitor [6-22] peptide
- 品牌:ABBIOTEC
- 产地:美国
- 货号:350008
- 价格: ¥询价/1 mg
- 发布日期: 2019-07-31
- 更新日期: 2024-03-29
产品详请
产地 | 美国 |
品牌 | ABBIOTEC |
货号 | 350008 |
保存条件 | store at -20°C |
保质期 | 两年个月 |
This peptide is a potent and competitive inhibitor of protein kinase A (PKA) with a Ki = 1.7 nM. The peptide sequence corresponds to residues 6-22 of human cAMP-dependent protein kinase inhibitor alpha (PKI-alpha) and is amidated at the C-terminus end. PKI-alpha interacts with the catalytic subunit of PKA after the cAMP-induced dissociation of its regulatory chains.Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH2 or TYADFIASGRTGRRNAI-NH2