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camkii substrate peptide
- 品牌:ABBIOTEC
- 产地:美国
- 货号:350007
- 价格: ¥询价/1 mg
- 发布日期: 2019-07-31
- 更新日期: 2024-04-25
产品详请
产地 | 美国 |
品牌 | ABBIOTEC |
货号 | 350007 |
保存条件 | store at -20°C |
保质期 | 两年个月 |
This peptide is a substrate (Km = 7.5 mM) for calcium/calmodulin-dependent protein kinase II (CaMKII), which belongs to the CAMK Ser/Thr protein kinase family. The sequence derives from the residues 1-10 of the glycogen synthase containing a phosphorylation site at Ser-7 within the R-X-X-S/T consensus site and is amidated at the C-terminus end. CaMKII is a prominent kinase in the central nervous system that functions in long-term potentiation and neurotransmitter release. Phosphorylation of the substrate is calcium and calmodulin dependent.Pro-Leu-Ser-Arg-Thr-Leu-Ser-Val-Ser-Ser-NH2 or PLSRTLSVSS-NH2